This is the combination of D-Mannose with Cranberry, Vitamin A, Vitamin C and Pre & Probiotics which provides side effect–free relief from urinary tract infections often caused by E. coli infection.
D-Mannose, Cranberry, Vitamin A, Vitamin C and Pre& Probiotics are formulated as an effective alternative to antibiotics for the treatment of often-recurring urinary tract infections (UTIs). Antibiotic therapy for UTIs can disrupt the natural balance of beneficial bacteria and contribute to the development of menacing antibiotic-resistant bacterial strains. Women need to be especially vigilant about maintaining a healthy flora balance not only in their digestive system, but in their bladder and urinary tract as well.
This supplement is specially formulated to support healthy urinary tract function by providing gentle cleansing while inhibiting the adhesion of toxic substances to urinary tract walls. Cranberries are an abundant source of flavonoids, including proanthocyanins, which exhibit anti-adhesion properties. It is this anti-adhesion effect that makes cranberries so effective for cleansing and supporting the urinary tract. D-Mannose is a simple sugar that occurs naturally in certain plants. Similar to proanthocyanins, D-Mannose exerts an anti-adhesion effect in the urinary tract that allows soluble waste products to be flushed out in the urine. Because insubstantial amounts are used by the body, D-Mannose doesn't interfere with healthy blood sugar regulation.

Urinary Tract Health:
Urinary Tract Infections (UTIs) are among the most common of all bacterial infections. Anyone of any age can have a UTI. However, young to middle-aged women who are sexually active are most often affected by UTIs. An infection occurs when microorganisms, usually bacteria from the digestive tract, cling to the opening of the urethra and begin to multiply. Most infections arise from one type of bacteria, Escherichia coli (E. coli), which normally live in the colon and causes about 80% of UTIs in adults. Symptoms of UTIs, both uncomfortable and debilitating, may include pain or burning with urination, the urge to urinate frequently while passing only small quantities of urine, tenderness or a feeling of heaviness in the lower abdomen, cloudy or foul-smelling urine, pain on one side of the back under the rib cage (flank pain), fever, chills, nausea and vomiting.
Most cases of UTIs are caused by the bacteria E. coli. This bacterium is normally present inside the digestive tract and on the skin surrounding the anus. In women, it is easier for the bacteria to travel to the urethra because the urethral opening is a lot closer to the anus than in men.
In order to cause an infection, bacteria must first adhere to the cells lining the urinary tract. They do these using hair-like fimbriae that protrude from their surfaces. The fimbriae attach to specific receptors on the cells.
D-mannose helps to prevent infections by interfering with the ability of the fimbriae to latch onto your cells.
In this combination Cranberry and D-Mannose create an effective dual anti-adherence formula.
Probiotics help maintain a healthy microbial balance throughout the digestive system.
FOS as prebiotic help nourish existing bacteria for feminine health.
Probiotic with Prebiotic together for Broader Microbial Support & a Healthy Feminine Tract.
Vitamin C limits the growth of some bacteria by acidifying the urine.
Vitamin A helps in refurbishing damaged tissues in the urinary bladder which speeds up healing and recovery process.

Indications & Usage:
  • Effective against both antibiotic susceptible and resistant strains of bacteria
  • Helps fight off acute UTI
  • Helps prevent UTI recurrence
  • Potent anti-inflammatory and diuretic effect
  • Helps maintain optimal vaginal, bladder, and urinary health
  • Promotes healthy balance of bacteria in the gut
  • Supports a healthy immune system and optimal digestive health
  • Helps relieve constipation, gas, and bloating
  • Promotes regular bowel movements

About composition:

Cranberry Extract:
Cranberry has been well studied for its ability to prevent and decrease the severity of urinary tract infections. It contains compounds called lectins that prevent bacteria from sticking to the walls of the urinary tract. The bacteria are then flushed out through the urine and do not lead to infection. Cranberry also acidifies the urine, which makes it an uncomfortable environment for bacteria to live and reproduce.
Cranberries also contain significant amounts of vitamin C, which is important for the healing of the lining of the urinary tract. Finally, the proanthocyanidins that are found in cranberry have been shown to have anti-cancer effects in laboratory testing.

D – Mannose:
D-Mannose is a monosaccharide, a simple sugar but unlike glucose it is absorbed eight times slower. Because it is hard for our bodies to absorb D-Mannose it passes straight to the blood stream, then through the kidneys into the bladder. Since it is not metabolized in the body like other sugars, it does not affect the blood sugar levels, and therefore is safe for the diabetic menu and does not cause weight gain.
D-mannose is a simple sugar that prevents adherence of certain bacterial strains to uro-epithelial cells of the bladder. It prevents 90% or more of UTIs that are caused by the bacteria E.coli.
D-Mannose has antibacterial, antiviral and antifungal properties. It plays a key role in the formation of cytokines—the chemicals that make you feel achy when you're sick. Cytokines, in turn, stimulate the immune system to fight the parasitic invader.

Probiotics:
Probiotics, or friendly bacteria, are the beneficial microbial flora we all need for optimal digestive and colon health. We all have them – the first probiotics being given to us during the process of breast feeding from our mothers, with our need for them never waning throughout our entire lives. Without health gut flora, poor assimilation of nutrients, intestinal irritation or constipation can result.
The probiotics L.rhamnosus, L.acidophilus and L. Salivarius specialized probiotic strain recognized for its effectiveness with antibiotic-resistant bacterial strains. L. rhamnonus is extremely resistant to stomach acids and produces compounds (surfactants) that disrupt pathogenic bacterial strains from adhering to the lining of the urinary tract.
Probiotics helps restore the balance of intestinal and vaginal bacteria, and may be particularly beneficial if you've taken antibiotics to help treat a urinary tract infection.

Lactobacillus acidophilus:
This probiotic bacterium has led many people to refer to probiotics simply as "acidophilus". It is the most prevalent in the human intestine and has been the most widely studied probiotic bacteria with research starting on L.acidophilus as long ago as 1925. The best researched single strain of acidophilus is probably the DDS-1 strain. This strain amongst other benefits has been shown to stimulate the immune system, increasing levels of interleukin-1 alpha (IL-1 alpha) and tumor necrosis factor-alpha (TNF-alpha) which suppress cancerous tumour growth. Other research has shown that L.acidophilus DDS-1 also alleviates lactose intolerance by producing significant amounts of the lactose digesting enzyme lactase, inhibits gastrointestinal pathogens by producing antimicrobial substances such as acidophilin and helps alleviate dermatitis and other skin conditions by altering gut flora amongst other things.

Lactobacillus rhamnosus:
Lactobacillus rhamnosus is a probiotic bacterium that has been receiving a growing amount of attention as a treatment for many illnesses in the form of the GG strain. Lactobacillus rhamnosus GG (LGG) now has a wealth of research backing its use, particularly for infectious and allergic conditions. A 2001 study reviewing information regarding probiotics and infectious diseases found that there is a large amount of data showing that Lactobacillus GG is an effective treatment for diarrhea caused by Clostridium difficile infection4. Another study testing the effectiveness of probiotics in preventing allergic illness found that Lactobacillus GG given prenatally to mothers with at least 1 first-degree relative and postnatally for 6 months to their infants reduced the incidence of atopic eczema by half compared to controls.

Lactobacillus salivarius:
L.salivarius has been repeatedly shown to inhibit the bacteria Helicobacter pylori (H.pylori) which is responsible for the creation of peptic ulcers. H.pylori interferes with stomach acid production and/or produces a toxin that directly contributes to ulcer formation. The usual treatment involves taking antibiotics but H.pylori may become resistant to them and there are side effects of prolonged antibiotic use due to the eradication of beneficial bacteria along with the pathogenic bacteria. It has been discovered that L.salivarius produces large amounts of lactic acid that completely inhibits the growth of H.pylori and reduces the associated inflammatory response. The first bacteriocin (natural antibiotic substance) to be isolated and studied at the genetic level was taken from a strain of L.salivarius.

Fructooligosaccharides (FOS):
FOS is a prebiotic. In a study using pigs, FOS was shown to increase butyrate concentrations in the large intestine. Butyrate is a short chain fatty acid (SCFA) that helps to maintain the health of the colon. FOS encourages and support re-colonisation by the friendly bacteria.

What are UTIs?
Vitamin A: Vitamin A contains beta – carotene, an organic compound found in plants that fights the invasion of bacteria. Beta – carotene strengthens cells to make the more resistant to bacteria.

Vitamin C:
Vitamin C has antioxidant attributes that helps our body absorb bioflavonoid. Bioflavonoid helps in removing toxic radicals thereby improving our body immunity that prevents bacterial growth in the urinary tract.It can have a bacteriostatic effect in the urine. This effect was shown to be mediated by the reduction of urinary nitrites to reactive nitrogen oxides rather than by lowering urinary pH.

Side Effects:
Cranberry juice and D-mannose have been associated with gastrointestinal upset, nausea, vomiting, and diarrhea in some individuals.

Precautions:
  • If pregnant or lactating, consult your dietician before taking this product
  • D-Mannose should not interfere with blood sugar regulation even for diabetics because so little is absorbed, though close monitoring is always advised. Consult your physician for more information

Storage:
Store in a cool, dry & dark place. Protected from direct sunlight.